Headline News

Prof. Mariko Okada was awarded the 2018 Commendations for Science and Technology by MEXT

The Ministry of Education, Culture, Sports, Science and Technology (MEXT)announced the recipients of the 2018 Commendations for Science and Technology. From Osaka University, eight faculty member received awards, including Prof. Mariko Okada of Institute for Protein Research.

Prof. Okada was awarded the Prize for Science and Technology (Research Category).

Name of Achievement: Research on cellular mechanisms based on experiments and mathematical models

 

Website of Osaka Univ.

http://www.osaka-u.ac.jp/en/news/topics/2018/04/20180412_01

 

Click here for more datails on Prof. Okada’s research

Publication:“Phosphorylation of an intrinsically disordered region of Ets1 shifts a multi-modal interaction ensemble to an auto-inhibitory state”

On 4th January 2018, a paper has been published from Nucleic Acids Research (IF=10.162) by the research team of Dr. Kota Kasahara (Ritsumeikan University), Dr. Masaaki Shiina, Prof. Kazuhiro Ogata (Yokohama City University), Prof. Junichi Higo and Prof. Haruki Nakamura (IPR, Osaka University), revealing the regulation mechanism of the intrinsically disordered region of Ets1 transcription factor due to phosphorylation of Ser residues by molecular simulation and biochemical studies.

 

Click here for more details

 

Science Agora 2017 -in Tokyo-

IPR, together with PDBj, Hiroshima City Univ.Ritsumeikan Univ. and Kwansei Gakuin Univ. will hold a booth at Science Agora 2017 organized by Japan Science and Technology Agancy (JST).

Date:
  • November 24 (Friday), 2017 (13:30〜18:00)
  • November 25 (Saturday) – November 26 (Sunday) (10:00〜16:00)
Venues:
Telecom Center Building, Odaiba Tokyo
5th floor Area D (innovating new knowledge by linking different fields), Booth No.65

“Shape” of proteins, which supporting the life

(The website linked from the title is displayed only in Japanese)
The aim of our exhibition is providing chances for various people to realize the diversity and importance of the “Shape” of proteins though experiences such as watching, feeling and constructing. We hope it helps them to deepen their understanding for biomolecules. The details of exhibition are as following:
  1. “Watching” by accessing PDBj database and browsing protein molecules with CG in sterically.
  2. “Feeling” by touching the molecule models made with a 3D printer
  3. “Constructing” by making molecules with paper crafts
We also introduce the methods and facilities such as synchrotrons and high resolution electron microscopes (Nobel Prize of this year was awarded for it!) to solve molecule shapes.

Research and Exchange between Ruhr University Bochum and IPR Strengthened

The Faculty of Biology and Biotechnology, Ruhr University Bochum (RUB) and the Institute for Protein Research, Osaka University (IPR) have concluded a cooperation agreement in October 2017. It is complementary to the existing cooperation between the two universities since 2010.

Publication: “Subtelomeres constitute a safeguard for gene expression and chromosome homeostasis”

Nucleic Acids Research Breakthrough article describes the biological role of subtelomeric sequences in chromosome maintenance and chromatin structure.

Research teams led by Dr. Junko Kanoh at Osaka University and by Kunihiro Ohta at the University of Tokyo (Japan), have described a study of the biological function of subtelomeric homologous (SH) sequences (and of subtelomeres more generally) through phenotypic analysis of a Schizosaccharomyces pombe (fission yeast) mutant in which all SH sequences in the genome were deleted.

 

NAR_Breakthrough.pdf

 

 

A paper by Dr. Gert-Jan Bekker has been published from Journal of Chemical Theory and Computation with its cover picture of the Issue 7, 2017.

A paper”Accurate Prediction of Complex Structure and Affinity for a Flexible Protein Receptor and its Inhibitor (http://pubs.acs.org/doi/abs/10.1021/acs.jctc.6b01127, DOI: 10.1021/acs.jctc.6b01127) by Dr. Gert-Jan Bekker, who is a Specially Appointed Assistant Professor in IPR, has been published from Journal of Chemical Theory and Computation (JCTC, IF=5.301) with its cover picture of the Issue 7, 2017.

 

Figure.jpg