Laboratories & Administration Office
- トップページ
- Laboratories & Administration Office
- Division of Protein Chemistry
Laboratory of Protein Organic Chemistry
member
| Director | Saburo AIMOTO Hideo AKUTSU(Guest Professor) |
|---|---|
| 准教授 | Toru KAWAKAMI |
| 助教 | Takeshi SATO Toshiaki HARA |
連絡先
| Tel | 81-6-6879-8601 |
|---|---|
| Fax | 81-6-6879-8603 |
研究概要
Our research goal is to develop the methods that enable the synthesis of a wide variety of proteins. To realize such synthesis we are developing chemical methods such as a thioester method and an extended native chemical ligation method. A hybrid method is also being developed in which chemical and biological means are used as the preparation of building blocks. The chemoselective ligation strategies are also being applied to the preparation of site-specifically modified peptides and membrane proteins for use in the analysis of protein-protein interaction.
<Fig.1>
A newly developed building block for protein synthesis that
contains an auto-activating unit, a Cys-Pro-OR residue.
<Fig.2>
Preparation of a peptide that contains a transmembrane and
juxtamembrane regionsfor use in the analysis of protein-protein
and protein-lipid bilayer interaction.
Contact:
