2024

• Arivarasan S., Chen, Z., Tang, Y., Ito, M., Fujita, Y., and Shinohara A. Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis.Scientific Reports, 14, 9550, 2024
• Matsuzaki, M., Shinohara, A., and Shinohara M. Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation. Nucleic. Acids Res. Feb 10:gkae083, 2024
• Jeong H. Joo, Soogil Hong, Mika Higashide, Eui-Hwan Choi, Seobin Yoon, Min-Su Lee, Akira Shinohara, Nancy Kleckner, and Keun P. Kim. Dynamic Arrangements of Replication Protein A-Single Stranded DNA in Meiotic Double-Strand Break Repair. Nucleic. Acids Res.Feb 10:gkae083, 2024
• Fajish, G.V., Challa, K., Sager S., V.P. Ajith, Mwaniki, S., Zhang, R., Fujita, Y., Ito, M., Nishant K.T. and Shinohara A. DNA double-strand breaks regulate the cleavage-independent release of Rec8-cohesin during yeast meiosis. Genes-to-Cells, 29, 86-98, 2024

2023

• Ito, M., Furukohri, A., Matsuzaki, M., Fujita, Y., and Shinohara A. FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and recombination. Nature Communications, 14, 6857. 2023
• Dash, S., Joshi, S., Ajith, V.P., Shinohara, A. and Nishant K.T. Heterozygosity alters Msh5 binding to meiotic chromosomes in the baker’s yeast.Genetics, iyad214, 2023
• Liu, S., Shinohara, A., and Furukohri, A. A Fanconi anemia-associated mutation in RAD51 compromises the coupling of DNA binding and ATPase activities. J. Biol. Chem. , 299. 105424, 2023
• Sato, T., and A. Shinohara. Characterizing interaction between the juxtamembrane region of the single transmembrane protein and membrane using chemically synthesized peptides. STAR Protocols, 4, 102454, 2023.
• Shinohara M., and A. Shinohara. The Msh5 complex shows homeostatic localization in response to DNA double-strand breaks in yeast meiosis. Frontiers in Cell and Developmental Biology, 11, 1170689. 2023.
• Sawant, P., Mwaniki, S., Fujita, Y., Ito, M., Furukohori, A., and Shinohara A., The role of conserved amino acid residues of Sae3 in Mei5-Sae3 complex for Dmc1 assembly in meiotic recombination. Genes, Genetics and Systems , 98, 45-52. 2023.
• Payero, L., Gioia M., Pannafino G., Raghavan V., Chen J.J., Momoh S., Scotland, M., Carol Manhart C., Ghanim F.V., Shinohara A., K.T. Nishant and E. Alani. Exo1 protects DNA nicks from the ligation to promote crossover formation during meiosis. PLos Biology, 21, 3002085, 2023.
• Ito, M., and A. Shinohara. Chromosome architecture and homologous recombination in meiosis. Frontiers in Cell and Developmental Biology, 10, 1097446. 2023.

2021

• Rao, H.B.D.P., Sato, T., Challa, K., Shinohara M. and A. Shinohara Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis. eLife, 10, e63119, 2021
• Takagi, T., Osumi, M., and A. Shinohara, Ultrastructural analysis in yeast reveals a meiosis-specific actin-containing nuclear bundle. Communications Biology, 4, 1009, 2021.
• G.N. Krishnaprasada, Sager S., V.P. Ajith, Shinohara, M., Lin, G., Chakraborty, P., Farnaz, A., Steinmetz, L.M., Shinohara, A. and Nishant K.T. The baker’s yeast Msh4-Msh5 binds to double-strand break hotspots distant to chromosome axis to promote crossovers. Genetics, 219, iyab102, 2021.
• Lee, M.-S., Higashide, M., Kei. C., Li, K., Hong, S., Lee, K., Shinohara, A., Shinohara, M., and K.P. Kim. The Synaptonemal Complex Central Region Modulates Crossover Pathways and Feedback Control of Meiotic Double-Strand Break Formation. Nuclei. Acids Res. 49, 7537-7553, 2021.
• Suetake, I., Nakazawa, S., Sato, K., Mutoh, R., Mishima, Y., Kawakami, T., Takei T., Watanabe M., Sakai N., Fujiwara T., Takui T., Miyata M., Shinohara A., Hojo H., and T. Arata. Structural dynamics of the chromo-shadow domain and chromodomain of HP1 bound to histone H3K9 methylated peptide, as measured by site-directed spin-labeling EPR spectroscopy. Biochem. Biophys. Res Commun. 567, 42-48, 2021
• Usui T., and A. Shinohara. Rad9, a 53BP1 ortholog of budding yeast, is insensitive to Spo11-induced double-strand breaks during meiosis. Frontiers in Cell and Developmental Biology, 9, 635583, 2021.

2020

• Zhu, Z., Bani, I., Shinohara, M. and A. Shinohara. SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis. Life Science Alliance, 4, e202000933. 2021.
• Woo, T-T., Chuang, C-N., Higashide, M., Shinohara, A., and Ting-Fang Wang. Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks. Nuclei. Acids Res. 48, 8474-8489. 2020.
• Zhang Y., Suzuki T., Li K., Gothwal S.K., Shinohara M., and A. Shinohara. Genetic interactions of histone modification machinery, Set1 and PAF1C, with the recombination complex, Rec114-Mer2-Mei4, in the formation of meiotic DNA double-strand breaks. International Journal of Molecular Sciences. 21, 2679. 2020.
• Tatebe, H., Lim, C.T., Konno, H., Shiozaki, K., Shinohara, A., Uchihashi, T. and Furukohri, A. Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge. Nature Communications, 11, 370, 2020
• Mishima, Y., Brueckner, L, Takahashi, S., Kawakami, T., Otani, J., Shinohara, A., Takeshita, K., Garvilles, R., Watanabe, M., Sakai, N.,Takeshima, H., Nishiyama, A., Nakanishi, M., Kyohei, A., Nakashima, K-I. Hojo, H., and I. Suetake. Enhanced processivity of Dnmt1 by mono-ubiquitinated histone H3. Genes-to-Cells, 25, 22-32. 2020

2019

• Sasanuma, H., Sabhan, H.M.S., Furihata, Y., Challa, K., Palmer, L. Gasser, S.M., Shinohara, M., and A. Shinohara, Srs2 helicase prevents the formation of aberrant DNA damage during late prophase I of yeast meiosis. Chromosoma, 128, 453-471. 2019.
• Shinohara M., Bishop, D.K., and A. Shinohara. DNA damage response clamp loader Rad24(Rad17) and Mec1(ATR) kinase distinctly control meiotic crossover formation. Genetics, 113. 1255-1269. 2019
• Challa, K., Fajish G.V., Shinohara, M., Klein, F., Susan M. Gasser, S.M., and A. Shinohara. Meiosis-specific prophase-like pathway controls cleavage-independent　release of cohesin by Wapl phosphorylation.PLoS Genetics, 15, e1007851. 2019
• Matsuzaki, K., Kondo, S., Ishikawa, T., and A. Shinohara, Human RAD51 paralogue, SWSAP1, fosters RAD51 filament by regulating the anti-recombinase, FIGNL1 AAA+ ATPase. Nature Communications, 10, 1407. 2019
• Bommi, J.R., Prasada Rao, HBDP., Challa, K., Higashide, M., Shinmyozu, K. Nakayama, J., Shinohara, M., and A. Shinohara Meiosis-specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope. Genes-to-Cells, 24, 94-106, 2019

important papers before 2018

• Shinohara, A., Ogawa H. and T. Ogawa. Rad51 protein involved in recombination and repair in S. cerevisiae is a RecA-like protein. Cell, 69. 457-470. 1992
　　
• Ogawa, T., Yu, X., Shinohara, A. and E. Egelman. The filament formed by the yeast Rad51 protein has a similar structure to the bacterial RecA filament. Science, 258, 1896-1899. 1993
　　
• Shinohara, A., Ogawa, H., Mastuda, Y. Ushio, N., Ikeo, K. and T. Ogawa. Human and mouse homologues of recombination genes of S. cerevisiae RAD51 and E. coli recA. Nature Genetics, 4, 239-243. 1993
　　
• Shinohara, A., Gasior, S., Ogawa, T., Kleckner, N. and D.K. Bishop. S. cerevisiae RecA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination. Genes-to-Cells, 2, 615-630. 1997
　　
• Shinohara, A. and T. Ogawa. Stimulation of Rad51-mediated recombination by Rad52 in S. cerevisiae. Nature, 391, 404-407. 1998
　　
• Shinohara, A., Shinohara, M., Ohta, T., Matsuda, S. and T. Ogawa. Rad52 forms ring structure and co-operate with RPA in single-strand DNA annealing. Genes-to-Cells, 3, 145-156. 1998
　　
• Bishop, D.K., Ear, U., Bhattacharyya, A., Calderone, C., Beckett, M., Weichselbaum, R. and A. Shinohara. Xrcc3 is required for assembly of Rad51-complexes in vivo. J. Biol. Chem., 273, 21482-21488. 1998
　　
• Takata, M., Sasaki, M., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchi-Iwai, Y., Shinohara, A., and S. Takeda. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in maintenance of chromosome integrity. EMBO J., 17, 5497-5508. 1998
　　
• Shinohara, M., Gasior, S., Bishop, D. and A. Shinohara. The Tid1/Rdh54 promotes the coordination of Rad51 and Dmc1 during meiotic recombination. Proc. Natl. Acad. Sci. USA, 97, 10941-10819. 2000
　　
• 33. Miyazaki T., Bressan, D.A., Shinohara, M., Haber, J.E. and A. Shinohara. In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair. EMBO. J. 23. 939-949, 2004
　　
• 35. Yamashita, K., Shinohara, M. and A. Shinohara. Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis. Proc. Natl.Acad, Sci. USA. 101. 11380-11385, 2004
　　
• 36. Hayase, A., Takagi, M., Miyazaki, T., Oshiumi, H., Shinohara, M. and A. Shinohara. A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1. Cell, 119. 927-940. 2004
　　
• 39. Shinohara, M., Oh, S.D., Hunter, N. and A. Shinohara. Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis. Nature Genetics. 40, 299-309, 2008.
　　
• 41. Conrad, M.N., Lee, C.-Y., Chao, G., Shinohara, M. Kosaka, H., Shinohara, A., Conchello, J.-A., and M. E. Dresser. Telomeres drive rapid movements regulated by chromosome status in meiotic prophase. Cell, 133, 1175-1187, 2008.
　　
• 42. Kosaka, H., Shinohara, M. and A. Shinohara. Csm4-dependent telomere movement on nuclear envelope promotes meiotic recombination. PLoS Genetics, 4, e1000196, 2008.
　　
• 48. Sasanuma, H. Tawramoto, M.S., Lao, J., Hosaka, H., Sanda, E., Suzuki, M., Yamashita, E., Hunter, N., Shinohara M. Nakagawa, A. and A. Shinohara. A new protein complex promoting the assembly of Rad51 filaments. Nature Communications.4, 1676, 2013.
　　
• 53. Shinohara, M, Hayashihara, K., Grubb, J.T., Bishop, D.K., and A. Shinohara. DNA damage response clamp contributes to chromosomal assembly of ZMM-SIC pro-crossover factors during meiosis. J. Cell. Sci. 128, 1494-1506, 2015.
　　
• 57. Challa, KK., Lee, MS., Shinohara, M., Kim, K.M and A. Shinohara. Rad61/Wpl1(Wapl), a cohesin regulator, controls chromosome compaction during meiosis. Nuclei. Acids Res. 44, 3190-3203. 2016.