From Prof. Y. Harada

Looking inside the cells that make up our body, various protein molecules are working there. In order to know about organisms, it is very important to investigate how protein molecules work. So far, we have developed a method for directly observing how protein molecules work using a microscope, and have investigated how proteins work well. Recently, we are also observing cells in order to understand the cells where proteins work. Little by little, I want to approach the wonders of life.

Our body is made up of many cells. The proper functioning of each cell allows us to live in good health. Knowing the state inside a cell and knowing what is happening inside a cell is very important for understanding life. Therefore, we are developing methods to measure the environment of the nano region inside the cell using small fluorescent diamond particles, measuring the local temperature inside the cell, and investigating how the temperature change affects the cell function. We also provide a fluorescence microscope that can image protein secretion from individual cells in real time, and are conducting collaborative research with multiple laboratories.

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Developing techniques for
intracellular temperature
measurement

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Quantum biosensing
using fluorescent
nanodiamond

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Analysis of immune
responses using
live-cell imaging of
secretion activity

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