Our aim

There exist various biological macromolecular assemblies consisting of proteins, nucleic acids, sugars, lipids, and other substances in living cells. These macromolecular assemblies play key roles in all living system. Our laboratory works on structure determination of biological macromolecular assemblies, as well as proteins, which play important roles in biological system, using X-ray crystallography. Development of tools for X-ray crystal structure determination of biological macromolecular assemblies is also one of our main works, including development and management of the beamline for macromolecular assemblies at SPring-8.

Our Research Interests

  Sturucture determination of biological macromolecular assemblies
  Developement of SR beamline for biological macromolecular assemblies
  Development of methodologies/technologies for X-ray crystallography
  Structure determination of biologically important proteins

Main Targets

  Rice dwarf virus
  Multi-drug efflux pump complex of P. aeruginosa
  Proteins working in brain and neuronal system