{"id":415,"date":"2015-06-09T12:06:37","date_gmt":"2015-06-09T03:06:37","guid":{"rendered":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/?page_id=415"},"modified":"2015-12-03T15:32:26","modified_gmt":"2015-12-03T06:32:26","slug":"theme","status":"publish","type":"page","link":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/en\/research\/theme\/","title":{"rendered":"Research Activities"},"content":{"rendered":"<ul class=\"research-themes\">\n<li><a title=\"Structural Life Science Research of a Novel Voltage-Sensing Protein Family\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/voltage-sensor\/\">Structural Life Science Research of a Novel Voltage-Sensing Protein Family<\/a><\/li>\n<li><a title=\"Structural Life Science Research of Viruses\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/virus\/\">Structural Life Science Research of Viruses<\/a><\/li>\n<li><a title=\"Structural Life Science Research of Nuclear Transport Machineries\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/kakuyusou\/\">Structural Life Science Research of Nuclear Transport Machineries<\/a><\/li>\n<li><a title=\"Structural Life Science Research of Multi-Drug Efflux Pump\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/yakuzai-haisyutu\/\">Structural Life Science Research of Multi-Drug Efflux Pump<\/a><\/li>\n<li><a title=\"Development of Using Synchrotron Radiation Beamline for Biological Macromolecular Assemblies\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/housyakou\/\">Development of Using Synchrotron Radiation Beamline for Biological Macromolecular Assemblies<\/a><\/li>\n<li><a title=\"Development Coherent Diffraction Imaging Technique using X-ray Free Electron Laser\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/x-ray\/\">Development Coherent Diffraction Imaging Technique using X-ray Free Electron Laser<\/a><\/li>\n<\/ul>\n<h2>Research Projects (representative)<\/h2>\n<ul>\n<li><a href=\"http:\/\/www.jst.go.jp\/kisoken\/crest\/en\/index.html\">JST-CREST<\/a> (<a href=\"http:\/\/www.jst.go.jp\/kisoken\/crest\/en\/research_area\/ongoing\/areah24-3.html\">Structural Life Science and Advanced Core Technologies for Innovative Life Science Research<\/a>) &#8220;<a href=\"http:\/\/www.jst.go.jp\/kisoken\/crest\/en\/project\/38\/14531882.html\">Structural Studies of the Proteins Working in Novel Cell Membrane Potential Signal<\/a>&#8221; (2014-)<\/li>\n<li><a href=\"http:\/\/www.jst.go.jp\/kisoken\/presto\/en\/index.html\">JST-PREST<\/a> (<a href=\"http:\/\/www.jst.go.jp\/presto\/struct-lifesci\/en\/index.html\">Structural Life Science and Advanced Core Technologies for Innovative Life Science Research<\/a>) &#8220;<a href=\"http:\/\/www.jst.go.jp\/presto\/struct-lifesci\/en\/theme\/3ki.html#R06\">Elucidation of Dynamical Structures of Membrane Voltage Sensor<\/a>&#8221; (Kohei Takeshita) (2014-)<\/li>\n<\/ul>\n<h2>Research Projects (As a Project Member)<\/h2>\n<ul>\n<li>Photon and Quantum Basic Research Coordinated Development Program by MEXT (Kunio Miki, Kyoto Univ.)\u00a0 (2013-)<\/li>\n<li>Platform for Drug Discovery, Informatics, and Structural Life Science by MEXT (Soichi Wakatsuki, KEK-PF) (2012-)<\/li>\n<li>Coordination Funds for Promoting Aerospace Utilization (Space Protein Project) by MEXT (Yoshihiro Urade, Univ. Tsukuba) (2014-)<\/li>\n<li>X-ray Free Electron Laser Priority Strategy Program by MEXT (Rapid Structure Determination System for Drug-Target Proteins Using the X-ray Free Electron Laser) (So Iwata, RIKEN\/Kyoto Univ.) (2013-)<\/li>\n<\/ul>\n<h2>Completed Projects<\/h2>\n<h3>X-ray Free Electron Laser Priority Strategy Program by MEXT (2012-2013)<\/h3>\n<p>&#8220;Development of Structure Determination Method for Biological Macromolecular Assemblies using Spherical Particles&#8221;<\/p>\n<p>We worked on development of structure determination method for biological macromolecular assemblies using spherical particles using X-ray free electron laser by SALCA. JAXA-<\/p>\n<h3><a href=\"http:\/\/www.tanpaku.org\/e_index.php\">Targeted Proteins Research Program<\/a> (2018-2012)<\/h3>\n<p>The Targeted Proteins Research Program is a national project promoted by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan. The program aims to reveal the structure and function of proteins that have great importance in both academic research and industrial application.<\/p>\n<p>We contributed the project in 4 targeted proteins and development of X-ray structure determination techniques.<\/p>\n<p>The detail is described here.<\/p>\n<h3>JAXA-GCF project &#8216;High-Quality Protein Crystallization Project on the Protein Structure and Function Analysis for Application&#8217; (2004-2008)<\/h3>\n<p>2004-2008\u5e74\u5ea6\u306e5\u5e74\u9593\u3001\u5b87\u5b99\u822a\u7a7a\u7814\u7a76\u958b\u767a\u6a5f\u69cb\uff08JAXA\uff09\u306e\u56fd\u969b\u5b87\u5b99\u30b9\u30c6\u30fc\u30b7\u30e7\u30f3\uff08ISS\uff09\u5fdc\u7528\u5229\u7528\u7814\u7a76\u62e0\u70b9\u63a8\u9032\u5236\u5ea6\u30fbISS \u5fdc\u7528\u5229\u7528\u7814\u7a76\u62e0\u70b9\u3068\u3057\u3066\uff0c\u300c\u30b5\u30d6\u30aa\u30f3\u30b0\u30b9\u30c8\u30ed\u30fc\u30e0\u69cb\u9020\u751f\u7269\u5b66\u306e\u5c55\u958b\u300d\u3092\u9032\u3081\u307e\u3057\u305f\uff0e<\/p>\n<p>\u8a73\u3057\u304f\u306f<a title=\"JAXA ISS \u5fdc\u7528\u5229\u7528\u7814\u7a76\u62e0\u70b9\" href=\"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/research\/theme\/jaxa-iss\/\">\u3053\u3053<\/a>\u304b\u3089<\/p>\n<h3><a href=\"http:\/\/www.tanpaku.org\/eng\/pdf\/project_overview.pdf\">Protein 3000<\/a>\uff082002-2006\u5e74\u5ea6\uff09<\/h3>\n<p>\u5927\u962a\u5927\u5b66\u305f\u3093\u3071\u304f\u8cea\u7814\u7a76\u6240\u3067\u306f\uff0c\u6587\u90e8\u79d1\u5b66\u7701\u300c\u30bf\u30f3\u30d1\u30af3000\u30d7\u30ed\u30b8\u30a7\u30af\u30c8 \u500b\u5225\u7684\u89e3\u6790\u30d7\u30ed\u30b0\u30e9\u30e0\uff08\u8133\u30fb\u795e\u7d4c\u7cfb\uff09\u300d\u306e\u4e2d\u6838\u6a5f\u95a2\u3068\u3057\u3066\uff0c2002-2006\u5e74\u5ea6\u306e5\u5e74\u9593\uff0c\u8133\u30fb\u795e\u7d4c\u7cfb\u306e\u69cb\u9020\u30d7\u30ed\u30c6\u30aa\u30df\u30af\u30b9\u306b\u95a2\u3059\u308b\u7814\u7a76\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u9032\u3081\u307e\u3057\u305f\uff0e<\/p>\n<p>\u8a73\u3057\u304f\u306f\u3053\u3053\u304b\u3089<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Structural Life Science Research of a Novel Voltage-Sensing Protein Family Structural Life Science Research of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":418,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"155","footnotes":""},"class_list":["post-415","page","type-page","status-publish","hentry","en-US"],"_links":{"self":[{"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/pages\/415","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/comments?post=415"}],"version-history":[{"count":15,"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/pages\/415\/revisions"}],"predecessor-version":[{"id":575,"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/pages\/415\/revisions\/575"}],"up":[{"embeddable":true,"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/pages\/418"}],"wp:attachment":[{"href":"http:\/\/www.protein.osaka-u.ac.jp\/rcsfp\/supracryst\/wp-json\/wp\/v2\/media?parent=415"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}