Welcome to the Laboratory for Biomolecular Modeling and Design
LBMAD is a research group in the Institute of Protein Research, Osaka University. We are interested in the development of computational methods for biomolecular modeling and conformational dynamics.
Iterative integration of experimental data and computational modeling
With rapid increase in experimental and structural data, more sophisticated strategies are required to gain a more realistic understanding of biomolecular mechanisms. By combining methodology from bioinformatics and data analysis, we use existing data for modeling and simulations. Such modeling and simulations methods are in turn useful analyzing and interpreting biophysical and biochemical experimental data. As we scale up the volume of data, we find that bioinformatics pipelines and data analysis methods are required, thus completing the circle.
Some topics of interest...
Some topics studied include and are not limited to: allostery, oligomerization, protein-protein interactions, conservation of structure and dynamics. Proteins studied: TIM Barrel fold proteins, PyrR, dihydrofolate reductase, leukotriene alpha-4 hydrolase, and many more.
Projects
Opportunities
We are looking for Masters' and PhD students. Please note that you will have to enroll into Osaka University and have to abide by their entrance requirements. Applying for scholarships is highly recommended.
For more details and examples on how to apply, please click here
Contact Us
Sandhya P. Tiwari
Independent Associate Professor
6F Laboratory for Biomolecular Modelling and Dynamics
Institute for Protein Research
Osaka University
3-2 Yamadaoka, Suita, Osaka 565-0871, Japan
sandhyatiwari[at]protein[dot]osaka-u[dot]ac[dot]jp
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