Publication
RECENT PUBLICATIONS
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*T. Kosugi, M. Tanabe, *N. Koga,
De novo design of ATPase based on the blueprint optimized
for harboring the P-loop motif, bioRxiv (2024).
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*N. Koga, R. Tatsumi-Koga,
Inventing Novel Protein Folds, Journal of Molecular Biology (2024).
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#K. Sakuma, #N. Kobayashi, T. Sugiki, T. Nagashima, T. Fujiwara,
K. Suzuki, N. Kobayashi, T. Murata, T. Kosugi, R. Tatsumi-Koga, *N.
Koga, Design of complicated all-α protein structures, Nature
Structural & Molecular Biology (2024).
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#S. Minami, #N. Kobayashi, T. Sugiki, T. Nagashima, T. Fujiwara,
R. Tatsumi-Koga, G. Chikenji, *N. Koga, Exploration of novel
αβ-protein folds through de novo design, Nature Structural &
Molecular Biology (2023).
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*T. Kosugi, T. Iida, M. Tanabe, R. Iino, and *N.Koga, De novo
design of allosteric control into rotary motor V1-ATPase by
restoring lost function, Nature Chemistry (2023).
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H. Murata, H. Imakawa, N. Koga, *G. Chikenji, The register shift
rules for βαβ-motifs for de novo protein design, PLoS ONE, 16(8),
e0256895 (24 pages) (2021).
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*A. Nakamura, N. Kobayashi, N. Koga, *R. Iino, Positive charge
introduction on the surface of thermostabilized PET hydrolase
facilitates PET binding and degradation, ACS Catalysis, 11,
8550-8564 (2021).
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M. Mitsumoto, K. Sugaya, K. Kazama, R. Nakano, T. Kosugi, *T.
Murata, *N. Koga, State-Targeting Stabilization of Adenosine A2A
Receptor by Fusing a Custom-Made De novo Designed α-Helical Protein,
Int. J. Mol. Sci, 22(23), 12906 (13 pages) (2021).
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*#N. Koga, #R. Koga, # G. Liu, J. Castellanos, G. *T.
Montelione, *D. Baker, Role of backbone strain in de novo design of
complex α/β protein structures, Nature Communications, 12:3921 (12
pages) (2021).