タンパク質有機化学研究室

出版物リスト

朝比奈 雄也 ORCID

  • Y. Asahina and H. Hojo, One Step Synthesis of Fmoc-Aminoacyl-N-alkylcysteine via the Ugi Four-Component Condensation Reaction. J. Org. Chem. 1458-1465 (2020). DOI:10.1021/acs.joc.9b02433
  • Y. Asahina, T. Kawakami and H. Hojo, Glycopeptide synthesis based on TFA-labile protection strategy and novel one-pot four-segment ligation for the synthesis of O-glycosylated histone H2A. Eur. J. Org. Chem, 1915-1920 (2019) (VIP Paper!). DOI:10.1002/ejoc.201801885
  • N. Takeda, T. Takei, Y. Asahina and H. Hojo, Sialyl Tn Unit with TFA-Labile Protection Realizes Efficient Synthesis of Sialyl Glycoprotein. Chem. Eur. J., 24, 2593–2597 (2018) (Hot Paper). DOI:10.1002/chem.201706127
  • K. Arai, T. Takei, M. Okumura, S. Watanabe, Y. Amagai, Y. Asahina, L. Moroder, H. Hojo, K. Inaba and M. Iwaoka, Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue. Angew. Chemie Int. Ed., 56, 5522–5526 (2017). DOI:10.1002/anie.201701654
  • P. Gunasekaran, S. R. Lee, S. M. Jeong, J. W. Kwon, T. Takei, Y. Asahina, G. Bang, S. Kim, M. Ahn, E. K. Ryu, H. N. Kim, K. Y. Nam, S. Y. Shin, H. Hojo, S. Namgoong, N. H. Kim and J. K. Bang. Pyrrole-Based Macrocyclic Small-Molecule Inhibitors That Target Oocyte Maturation. ChemMedChem, 12, 580–589 (2017). DOI:10.1002/cmdc.201700048
  • Y. Asahina, T. Kawakami, H. Hojo. One-pot native chemical ligation by combination of two orthogonal thioester precursors. Chem. Commun., 53, 2114 (2017). DOI:10.1039/c6cc10243c
  • Y. Asahina. Chemoenzymatic Synthesis of Glycoprotein Using the Peptide Ligation Chemistry. Trends Glycosci. Glycotechnol., 27, E15 or J15 (日本語版) (2015). DOI:10.4052/tigg.1414.4E(英語版), 10.4052/tigg.1414.4J(日本語版)
  • Y. Asahina, S. Komiya, A. Ohagi, R. Fujimoto, H. Tamagaki, K. Nakagawa, T. Sato, S. Akira, T. Takao, A. Ishii, Y. Nakahara, H. Hojo. Chemical Synthesis of O-glycosylated human interleukin-2 by the reverse polarity protection strategy. Angew. Chem. 54, 8226-8230 (2015). DOI:10.1002/anie.201501847
  • Y. Asahina, K. Nabeshima, H. Hojo. Peptidyl N-alkylcysteine as a peptide thioester surrogate in the native chemical ligation. Tetrahedron Lett., 56, 1370-1373 (2015) . DOI:10.1016/j.tetlet.2015.01.095
  • Y. Asahina, R. Fujimoto, A. Suzuki, H. Hojo. Synthesis of Fmoc-Thr Unit Carrying Core 1 O-Linked Sugar With Acid-Sensitive O-Protecting Group and Its Application to the Synthesis of Glycosylated Peptide Thioester. J. Carbohydr. Chem. 34, 12-27 (2015) . DOI:10.1080/07328303.2014.977909
  • T. Takei, Y. Urabe, Y. Asahina, H. Hojo, T. Nomura, K. Dedachi, K. Arai, M. Iwaoka. Model Study Using Designed Selenopeptides on the Importance of the Catalytic Triad for the Antioxidative Functions of Glutathione Peroxidase. J. Phys. Chem. B, 118, 492-500 (2014) . DOI:10.1021/jp4113975
  • Y. Asahina, M. Kanda, A. Suzuki, H. Katayama, Y. Nakahara, H. Hojo. Fast Preparation of an N-Acetylglucosaminylated Peptide Segment for the Chemoenzymatic Synthesis of a Glycoprotein. Org. Biomol. Chem., 11, 7199-7207 (2013). DOI:10.1039/c3ob41565a
  • Y. Asahina, S. Kamitori, T. Takao, N. Nishi, H. Hojo. Chemoenzymatic Synthesis of the Immunoglobulin Domain of Tim-3 Carrying a Complex-Type N-Glycan by Using a One-pot Ligation. Angew. Chem. Int. Ed., 52, 9733-9737 (2013). DOI:10.1002/anie.201303073
  • H. Hojo, H. Tanaka, M. Hagiwara, Y. Asahina, A. Ueki, H. Katayama, Y. Nakahara, A. Yoneshige, J. Matsuda, Y. Ito, Y. Nakahara. Chemoenzymatic Synthesis of Hydrophobic Glycoprotein. Synthesis of Saposin C Carrying Complex-type Carbohydrate. J. Org. Chem., 77, 9437-9446 (2012). DOI:10.1021/jo3010155
  • H. Katayama, Y. Asahina, H. Hojo. Chemical Synthesis of the S-Linked Glycopeptide, Sublancin. J. Pept. Sci. 17, 818-821 (2011). DOI:10.1002/psc.1406
  • H. Hojo, H. Kobayashi, R. Ubagai, Y. Asahina, Y. Nakahara, H. Katayama, Y. Ito, Y. Nakahara. Efficient Preparation of Fmoc-aminoacyl-N-ethylcysteine Unit, a Key Device for the Synthesis of Peptide Thioesters. Org. Biomol. Chem., 9, 6807-6813 (2011). DOI:10.1039/c1ob05831b
  • M. Hagiwara, M. Dohi, Y. Nakahara, K. Komatsu, Y. Asahina, A. Ueki, H. Hojo, Y. Nakahara, Y. Ito, Synthesis of Biantennary Complex-type Nonasaccharyl Asn Building Blocks for Solid-phase Glycopeptide Synthesis. J. Org. Chem., 76, 5229-5239 (2011). DOI:10.1021/jo200149d