- Kenta Nagahama, Toshiki Takei, Shun Ito, Toshifumi Takao, Hironobu Hojo, Daiji Kiyozumi, Chemistry – A European Journal,
Chemical Synthesis of NICOL, A Coligand Secreted Protein Mediating Mammalian Male Reproductive Tract Trans‐luminal Signaling
doi: https://doi.org/10.1002/chem.202501588
- Sota Okazaki, Yoshihide Hattori, Nana Sakata, Masaya Goto, Sarino Kitayama, Hiroko Ikeda, Toshiki Takei, Shigeru Shimamoto, Yuji Hidaka，
Chemistry 7(4) 111-111 2025年6月30日
Synthesis and Cancer Cell Targeting of a Boron-Modified Heat-Stable Enterotoxin Analog for Boron Neutron Capture Therapy (BNCT)
doi: 10.3390/chemistry7040111
- Nana Sakata, Shigeru Shimamoto, Yuri Murakami, Orika Ashida, Toshiki Takei, Mitsuhiro Miyazawa, Yuji Hidaka
Molecules 29(22) 5476-5476 2024年11月20日
Mutational Analysis of Substrate Recognition in Trypsin-like Protease Cocoonase: Protein Memory Induced by Alterations in Substrate-Binding Site
doi: https://doi.org/10.3390/molecules29225476
- Masatomo So, Misaki Ono, Shigeki Oogai, Minako Kondo, Kaede Yamazaki, Charlotte Nachtegael, Hiroshi Hamajima, Risa Mutoh, Masaki Kato, Hisaya Kawate, Tomoyuki Oki, Yasushi Kawata, Shiho Kumamoto, Noritaka Tokui, Toshiki Takei, Kuniyoshi Shimizu, Akio Inoue, Naoki Yamamoto, Motoko Unoki, Kenichi Tanabe, Kinichi Nakashima, Hiroyuki Sasaki, Hironobu Hojo, Yasuo Nagata, Isao Suetake, Bioscience, Biotechnology, and Biochemistry, Volume 88, Issue 11, November 2024,
Inhibitory effects of extracts from Eucalyptus gunnii on α-synuclein amyloid fibrils
doi: https://doi.org/10.1039/bbb/zbae114
- Ying He, Toshiki Takei, Luis Moroder, Hironobu Hojo, Unexpected metathesis in diselenide-substituted biologically active peptides Org. Biomol. Chem.
doi: https://doi.org/10.1039/d4ob00921e
- S. Mitsunaga, N. Okumura, T. Takei, T. Takao, H. Tsubouchi, K. Nakata, M. Nakamura, Y. Kitahata, H. Motobayashi, M. Ikeda, M. Nakazato,
Identification of a urinary CD276 fragment for detecting resectable pancreatic cancer using a C-terminal proteomics strategy
DOI: 10.1038/s41598-024-65093-2
- A. Yamada, T. Takei, T. Kawakami, Y. Taniguchi, K. Sekiguchi, H. Hojo, Application of cysteinyl prolyl ester for the synthesis of cyclic peptides containing RGD sequence and their biological activity measurement, Front. Chem.12:1391678.
doi: https://doi.org/10.3389/fchem.2024.1391678
- I. Suetake, K. Sato, T. Sugishita, Y. Mishima, T. Takei, T. Fujiwara, R. Mutoh, A. Shinohara, T. Takui, M. Miyata, H. Hojo, T. Arata, Dynamics of the HP1 Hinge Region with DNA Measured by Site-Directed Spin Labeling-EPR Spectroscopy, Applied Magnetic Resonance, 54, 119-141, 2023.
doi: 10.1007/s00723-022-01519-2
- Md Nurul Islam, WD. Zhang, K. Sakai, Y. Nakazato, R. Tanida, H. Sakoda, T. Takei, T. Takao, M. Nakazato,
Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice
DOI: 10.1016/j.peptides.2022.170763
- T. Takei, H. Tanaka, L. Moroder, H. Hojo Chemical synthesis of per-selenocysteine human epidermal growth factor, J Pept Sci. 2022;e3464.
DOI: 10.1002/psc.3464
- I. Suetake, S. Nakazawa, K. Sato, R. Mutoh, Y. Mishima, T. Kawakami, T. Takei, M. Watanabe, N. Sakai, T. Fujiwara, T. Takui, M. Miyata, A. Shinohara, H. Hojo, T. Arata, Structural dynamics of the chromo-shadow domain and chromodomain of HP1 bound to histone H3K9 methylated peptide as measured by site-directed spin-labeling EPR spectroscopy, Biochem. Biophys. Res. Commun., 567 (2021) 42-48.
DOI:10.1016/j.bbrc.2021.06.010
- H. Hojo, T. Takei, Y. Asahina, N. Okumura, T. Takao, M. So, I. Suetake, T. Sato, A. Kawamoto, Y. Hirabayashi, Total synthesis and structural characterization of caveolin-1, Angewandte Chem. Int. Ed., 56, 14239-14242.
DOI: 10.1002/anie.202100826
- T. Takei, T. Ando, T. Takao, Y. Ohnishi, G. Kurisu, M. Iwaoka, H. Hojo, Chemical synthesis of ferredoxin with 4 selenocysteine residues using a segment condensation method, Chem. Commun., 2020, 56, 14239-14242.
DOI: 10.1039/d0cc06252a
- S. Shimodira, T.Takei, H. Hojo, M. Iwaoka, Synthesis
of selenocysteine-containing cyclic peptides via tandem N-to-S acyl
migration and intramolecular selenocysteine-mediated native chemical
ligation, Chem. Commun., 2018, 54,
11737-11740, DOI:
10.1039/c8cc06805d
- K. Arai,
T. Takei, R. Shinozaki, M. Noguchi, S. Fujisawa, H. Katayama, L. Moroder,
S. Ando, M. Okumura, K. Inaba, H. Hojo, M. Iwaoka, Characterization and optimization of two-chain
folding pathways of insulin via native chain assembly, COMMS CHEM
(2018)1:26, DOI:
10.1038/s42004-018-0024-0
- N. Takeda,
T. Takei, Y. Asahina, and H. Hojo,
Sialyl Tn Unit with TFA-Labile Protection
Realizes Efficient Synthesis of Sialyl
Glycoprotein Chem. Eur.J. 2018, 24,2593 –2597, DOI:
10.1002/chem.201706127
- T. Takei, T. Andoh,
T. Takao, H. Hojo, One-Pot Four-Segment Ligation using Seleno- and Thioesters: Synthesis of Superoxide
Dismutase, Angewandte Chem. Int. Ed. 56, 15708 –15711 (2017). DOI:
10.1002/anie.201709418
- P.
Gunasekaran, S.R. Lee, S.M. Jeong, J.W. Kwon, T.
Takei, Y. Asahina, G. Bang, S. Kim, M. Ahn, E.K. Ryu, H.N. Kim, K.Y. Nam, S.Y. Shin, H. Hojo, S. Namgoong, N.H. Kim,
J.K. Bang, Pyrrole-based macrocyclic small-molecule inhibitors that target
oocyte maturation, ChemMedChem,
12, 580-589 (2017). DOI:
10.1002/cmdc.201700048
- K. Arai,
T. Takei, M. Okumura, S. Watanabe, Y. Amagai, Y.
Asahina, L. Moroder, H. Hojo,
K. Inaba, M. Iwaoka, Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue, Angewandte Chem. Int. Ed. 56, 5522-5526
(2017). DOI:
10.1002/anie.201701654
- T. Takei, Y. Urabe, Y. Asahina, H. Hojo, T. Nomura, K. Dedachi, K. Arai, M. Iwaoka. Model Study Using Designed Selenopeptides on the Importance of the Catalytic Triad for the Antioxidative Functions of Glutathione Peroxidase. J. Phys. Chem. B, 118, 492-500 (2014) . DOI:10.1021/jp4113975
