(An IPR seminar series supported by WPI PRIMe and ASPiRE)

Date & Venue

• Date: Friday, November 22, 2024, 16:30 – 18:00
• Venue: 2nd Floor Medium Conference Room, Institute for Protein Research (Suita Campus, Osaka University) + Zoom
• Zoom Participation: If you would like to join via Zoom, please contact us at the addresses below.
  Meeting ID: 849 9164 5171
  Passcode: 098186

Presentation Information

Title: What can we learn from SAXS data? An example of complementary analysis with MD simulation

Speaker: Mao Oide, PhD.
Assistant Professor, Lab for CryoEM Structural Biology

Abstract

Molecular dynamics simulation enables us to sample dynamic structures of biomolecules with high spatio-temporal resolution. However, due to the difficulties of reproducing the real ensemble from MD simulation, it is important to compare with experimental data.

Among various experimental methods, Small-angle X-ray scattering (SAXS) can provide information on structural ensemble in solution at ambient temperature without any observational bias, even though structural information encoded in the profile is limited to low-resolution. In fact, SAXS data can also reveal a variety of molecular properties.

In this talk, the principle of the measurement and analysis will be briefly explained, and then the study of molecular dynamics using SAXS and MD calculations will be presented.

All are welcome!

Contact

Sandhya P. Tiwari
Email: sandhyatiwari[at]protein.osaka-u.ac.jp (Please replace [at] with @)

Ai Shinobu
Email: shinobu.ai.prime[at]osaka-u.ac.jp (Please replace [at] with @)

Flyer

You can view the flyer from the link below.