Achievements
list
Authors
Title
Journal
Taro Chaya, Yamato Maeda, Ryo Sugimura, Haruka Yamamoto, Hidemasa Kato, Takahisa Furukawa
Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation
Journal of Biological Chemistry
https://doi.org/10.1016/j.jbc.2022.101686
https://www.jbc.org/article/S0021-9258(22)00735-9/fulltext
Ryotaro Tsutsumi, Taro Chaya, Toshinori Tsujii, Takahisa Furukawa
The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis
Journal of Biological Chemistry
https://doi.org/10.1016/j.jbc.2022.101686
https://www.jbc.org/article/S0021-9258(22)00126-0/fulltext
Taro Chaya, Hiroshi Ishikane, Leah R Varner, Yuko Sugita, Yamato Maeda, Ryotaro Tsutsumi, Daisuke Motooka, Daisuke Okuzaki, Takahisa Furukawa
Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity
HUMAN MOLECULAR GENETICS
https://doi.org/10.1093/hmg/ddab268
https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab268/6368510
Daichi Gyoten, Shinji Ueno, Satoshi Okado, Taro Chaya, Shunsuke Yasuda, Takeshi Morimoto, Mineo Kondo, Kazuhiro Kimura, Takaaki Hayashi, Bart P Leroy, Se Joon Woo, Ryo Mukai, Kwangsic Joo, Takahisa Furukawa
Broad locations of antigenic regions for anti-TRPM1 autoantibodies in paraneoplastic retinopathy with retinal ON bipolar cell dysfunction
Experimantal Eye Research
https://doi.org/10.1016/j.exer.2021.108770
https://www.sciencedirect.com/science/article/abs/pii/S0014483521003365?via%3Dihub
Shun Kubo, Haruka Yamamoto, Naoko Kajimura, Yoshihiro Omori, Yamato Maeda, Taro Chaya, Takahisa Furukawa
Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity
Scientific Reports
https://doi.org/10.1038/s41598-021-83781-1
https://www.nature.com/articles/s41598-021-83781-1
Takefumi Sugiyama, Haruka Yamamoto, Tetsuo Kon, Taro Chaya, Yoshihiro Omori, Yutaka Suzuki, Kentaro Abe, Dai Watanabe, Takahisa Furukawa
The potential role of Arhgef33 RhoGEF in foveal development in the zebra finch retina
Scientific Reports
https://doi.org/10.1038/s41598-020-78452-6
https://www.nature.com/articles/s41598-020-78452-6
Yuko Sugita, Haruka Yamamoto, Yamato Maeda, Takahisa Furukawa
Inluence of aging on the retina and visual motion processing for optokineic responses in mice
Frontiers in Neuroscience
https://doi.org/10.3389/fnins.2020.586013
https://www.frontiersin.org/articles/10.3389/fnins.2020.586013/full
Tetsuo Kon, Takahisa Furukawa
Origin and evolution of the Rax homeobox gene by comprehensive evolutionary analysis
FEBS open bio
https://doi.org/10.1002/2211-5463.12832
https://febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.12832
Yuko Sugita, Kenichiro Miura, Takahisa Furukawa
Retinal ON and OFF pathways contribute to initial optokinetic responses with different temporal characteristics
European Journal of Neuroscience
https://doi.org/10.1111/ejn.14697
https://onlinelibrary.wiley.com/doi/full/10.1111/ejn.14697?af=R
Haruka Yamamoto, Tetsuo Kon, Yoshihiro Omori, Takahisa Furukawa
Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development
Cell Reports
https://doi.org/10.1016/j.celrep.2019.212.072
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31729-2
Taro Chaya, Ryotaro Tsutsumi, Leah Rie Varner, Yamato Maeda, Satoyo Yoshida, Takahisa Furukawa
Cul3‐Klhl18 ubiquitin ligase modulates rod transducin translocation during light‐dark adaptation
EMBO J.
https://doi.org/10.15252/embj.2018101409
https://www.embopress.org/doi/10.15252/embj.2018101409
Takashi Kozuka, Yoshihiro Omori, Satoshi Watanabe, Etsuko Tarusawa, Haruka Yamamoto, Taro Chaya, Mayu Furuhashi, Makiko Morita, Tetsuya Sato, Shinichi Hirose, Yasuyuki Ohkawa, Yumiko Yoshimura, Takatoshi Hikida & Takahisa Furukawa
miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation
Scientific Reports
https://doi.org/10.1038/s41598-019-38910-2
https://www.nature.com/articles/s41598-019-38910-2
Ryotaro Tsutsumi, Taro Chaya, Takahisa Furukawa
Enriched expression of the ciliopathy gene Ick in cell proliferating regions of adult mice
Gene Expression Patterns
doi:10.1016/j.gep.2018.04.005
https://www.sciencedirect.com/science/article/pii/S1567133X18300140
Akiko Ueno, Yoshihiro Omori, Yuko Sugita, Satoshi Watanabe, Taro Chaya, Takashi Kozuka, Tetsuo Kon, Satoyo Yoshida, Kenji Matsushita, Ryusuke Kuwahara, Naoko Kajimura, Yasushi Okada, Takahisa Furukawa
Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity
Cell Reports 22, 3548–3561 March 27, 2018
doi:10.1016/j.celrep.2018.03.007
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30321-8
Michio Miyajima, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Matteo M Guerrini, Yumi Tsutsui, Mikako Maruya, Alexis Vogelzang, Kenji Chamoto, Kurara Honda, Takatoshi Hikida, Satomi Ito, Hongyan Qin, Rikako Sanuki, Keiichiro Suzuki, Takahisa Furukawa, Yasushi Ishihama, Fumihiko Matsuda, Makoto Suematsu, Tasuku Honjo and Sidonia Fagarasan
Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior
Nature Immunology.
doi:10.1038/ni.3867
https://www.nature.com/articles/ni.3867
Kozuka T, Chaya T, Tamalu F, Shimada M, Fujimaki-Aoba K, Kuwahara R, Watanabe SI, Furukawa T.
The TRPM1 channel is required for development of the rod ON bipolar cell-AII amacrine cell pathway in the retinal circuit.
J Neurosci. 2017 Sep 12.
pii: 0824-17. http://www.jneurosci.org/content/early/2017/09/12/JNEUROSCI.0824-17.2017
Omori Y, Kubo S, Kon T, Furuhashi M, Narita H, Kominami T, Ueno A, Tsutsumi R, Chaya T, Yamamoto H, Suetake I, Ueno S, Koseki H, Nakagawa A and Furukawa T
Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity.
Proc Natl Acad Sci U S A. 2017.
Taro Chaya, Akihiro Matsumoto, Yuko Sugita, Satoshi Watanabe, Ryusuke Kuwahara, Masao Tachibana and Takahisa Furukawa
Versatile functional roles of horizontal cells in the retinal circuit.
Sci Rep. 2017 Jul 17;7(1):5540.
Okamoto S, Chaya T, Omori Y, Kuwahara R, Kubo S, Sakaguchi H and Furukawa T
Ick ciliary kinase is essential for planar cell polarity formation in inner ear hair cells and hearing function
J. of Neurosci, 2017, Feb 22;37(8): 2073-2085.
Irie S, Sanuki R, Muranishi Y, Kato K, Chaya T, Furukawa T
Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse Retina.
Mol Cell Biol 35:2583–2596.
doi:10.1128/MCB.00048-15.
Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T.
Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.
PLoS One. 2015 Jun 8;10(6):e0128422.
doi: 10.1371/journal.pone.0128422. eCollection 2015.
Watanabe S, Sanuki R, Sugita Y, imai W, Yamazaki R, Kozuka T, Ohsuga M, Furukawa T.
Prdm13 Regulates Subtype Specification of Retinal Amacrine Interneurons and Modulates Visual Sensitivity.
J. of Neurosci, 2015, May 20;35(20): 8004-20.
Chaya T, Omori Y, Kuwahara R, Furukawa T.
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
EMBO J. 2014,
doi:10.1002/embj.201488175
Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW & Wijnholds J
Targeted ablation of Crb2 in Photoreceptor Cells induces Retinitis Pigmentosa.
Hum Mol Genet. 2014,
doi:10.1093/hmg/ddu048
Mizuhashi K, Kanamoto T, Moriishi T, Muranishi Y, Miyazaki T, Terada K, Omori Y, Ito M, Komori T, Furukawa T
Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.
Hum Mol Genet. 2014,
doi:10.1093/hmg/ddu007
Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A & Watanabe S
Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.
Proc Natl Acad Sci USA, 2014,111(10): 3751-3756.
Kanda A, Noda K, Yuki K, Ozawa Y, Furukawa T, Ichihara A & Ishida S
Atp6ap2/(Pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.
J. of Neurosci, 2013, 33(49): 19341-19351.
Yamazaki D, Funato Y, Miura J, Sato S, Toyosawa S, Furutani K, Kurachi Y, Omori Y, Furukawa T, Tsuda T, Kuwabata S, Mizukami S,Kikuchi K & Miki H
Basolateral Mg2+ Extrusion via CNNM4 Mediates, Transcellular Mg2+, Transport across Epithelia: A Mouse Model.
PLOS Gene. 2013, 9(12): e1003983.
Sugita Y, Miura K, Araki F, Furukawa T, Kawano & K.Eur
Contributions of retinal direction-selective ganglion cells to optokinetic responses in mice.
Eur J Neurosci. 2013, 38(6): 2823-31.
Eberhart A, Feodorava Y, Song C, Wanner G, Kiseleva E, Hake S, Furukawa T, Kimura H, Schotta G, Leonhardt H, Joffe B & Solovei I
Epigenetics of eu- and heterochromatin in inverted and conventional nuclei.
Chromosome Res. 2013, 20(5): 535-554.
Watanabe S, Sanuki R, Ueno S, Koyasu T, Hasegawa T, Furukawa T
Tropisms of AAV for subretinal delivery to the neonatal mouse retina and its application for in vivo rescue of developmental photoreceptor disorders.
PLoS One. 2013; 8(1):e54146.
Katoh K, Yamazaki R, Onishi A, Sanuki R, Furukawa T.
G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.
J. of Neurosci. 2012, Dec 5;32(49):17658-70.
Muranishi Y & Furukawa T
BAC-Dkk3-EGFP Transgenic Mouse: An In Vivo Analytical Tool for Dkk3 Expression.
J Biomed Biotechnol. 2012:973140.
Peachey NS, Pearring JN, Bojang P, Jr., Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, & Gregg RG
Depolarizing Bipolar Cell Dysfunction due to a Trpm1 Point Mutation.
J Neurophysiol. 2012, 108(9):2442-2451.
Ochocinska MJ, Muñoz EM, Veleri S, Weller JL, Coon SL, Pozdeyev N, Michael Iuvone P, Goebbels S, Furukawa T & Klein DC
NeuroD1 is required for survival of photoreceptors but not pinealocytes: Results from targeted gene deletion studies.
J Neurochem. 2012, 123(1):44-59.
Omori Y, Araki F, Chaya T, Kajimura N, Irie S, Terada K, Muranishi Y, Tsujii T, Ueno S, Koyasu T, Tamaki Y, Kondo M, Amano S, Furukawa T.
Presynaptic Dystroglycan-Pikachurin Complex Regulates the Proper Synaptic Connection between Retinal Photoreceptor and Bipolar Cells.
J. of Neurosci. 2012 May 2;32(18): 6126-6137.
Muranishi Y, Terada K, Inoue T, Katoh K, Tsujii T, Sanuki R, Kurokawa D, Aizawa S, Tamaki Y, Furukawa T.
An Essential Role for RAX Homeoprotein and NOTCH–HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination.
J. of Neurosci. 2011, 31(46): 16792-16807
Sanuki, R., Onishi, A., Koike C., Muramatsu R., Watanabe S., Muranishi Y., Irie S., Uneo S., Koyasu T., Matsui R., Chérasse Y., Urade Y., Watanabe D., Kondo M., Yamashita T. & Furukawa T.
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression, Nature Neuroscience, 14, 1125–1134 (2011)
Pearring, J., Bojang Jr., P., Shen, Y., Koike, C., Furukawa, T., Nawy, S. & Gregg, R.
A Role for Nyctalopin, a Small Leucine-Rich Repeat Protein, in Localizing the TRP Melastatin 1 Channel to Retinal Depolarizing Bipolar Cell Dendrites.
J. of Neurosci. 31(27), 10060-10066 (2011)
*Omori, Y., *Katoh, K., *Sato, S., Muranishi, Y., Chaya, T., Onishi, A., Minami, T., Fujikado, T., & Furukawa, T.
Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.
PLoS ONE, 6(5), e19685 (2011)
(*First three authors contributed equally to this work.)
*Kondo, M., *Sanuki, R., Ueno, S., Nishizawa, Y., Hashimoto, N., Ohguro, H., Yamamoto, S., Machida, S., Terasaki, H., Adamus, Grazyna., & Furukawa, T.,
Indentification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction.
PLoS ONE, 6(5), e19911 (2011)
(*These authors contributed equally to this work.)
Okada, I., Hamanoue, H., Terada, K., Tohma, T., Megarbane, A., Chouery, E., Abou Ghoch, J., Jalkh, N., Cogulu, O., Ozkinay, F., Horie, K., Takeda, J., Furuichi, T., Ikegawa, S., Nishiyama, K., Miyatake, S.,
Nishimura, A., Mizuguchi, T., Niikawa, N., Hirahara, F., Kaname, T., Yoshiura, K., Tsurusaki, Y., Doi, H., Miyake, N., Furukawa, T., Matsumoto, N. & Saitsu, H.
SMOC1 is essential for ocular and limb development in humans and mice.
Am. J. Hum. Genet.,88, 1-12 (2010)
Omori Y., Chaya T., Katoh K., Kajimura N., Sato S., Muraoka K., Ueno S., Koyasu T., Kondo M., & Furukawa T.
Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.
Proc. Natl. Acad. Sci. USA, 2010 Dec. 8
Katoh, K., Omori Y., Onishi A., Sato S., Kondo M. & Furukawa, T. Blimp1 Suppresses Chx10 Expression in Differentiating Retinal Photoreceptor Precursors to Ensure Proper Photoreceptor Development.
J. of Neurosci, 30(19):6515-6526 (2010)
Nakamura, M., Sanuki, R., Yasuma, R, T., Onishi, A., Nishiguchi, M, K., Kadowaki, M., Kondo, M., Miyake, Y. & Furukawa, T.
TRPM1 mutations are associated with the complete form of congenital stationary night blindness.
Mol. Vision 16:425-437 (2010)
Katahira, T., Nakagiri, S., Terada, K. & Furukawa, T.
Secreted factor FAM3C (ILEI) is involved in retinal laminar formation.
BBRC, 392(3), 301-306 (2010)
Muranishi, Y., Sato, S., Inoue, T., Ueno, S., Koyasu, T., Kondo, M. & Furukawa, T.
Gene expression analysis of embryonic photoreceptor precursor cells using BAC-Crx-EGFP transgenic mouse.
BBRC, 392(3), 317-322 (2010)
Sanuki, R., Omori, Y., Koike, C., Sato, S. & Furukawa, T.
Panky, a novel photoreceptor-specific ankyrin repeat protein, is a transcriptional cofactor that suppresses CRX-regulated photoreceptor genes.
FEBS Letters, 584, 753-758 (2009)
Koike, C., Obara, T., Uriu, Y., Numata, T., Sanuki, R., Miyata, K., Koyasu, T., Ueno, S., Funabiki, K., Tani, A., Ueda, H., Kondo, M., Mori Y., Tachibana, M. & Furukawa, T.
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.
Proc. Natl. Acad. Sci. USA, 2009 Dec.4. Epub ahead of print (2009)
Kanamoto, T., Mizuhashi, K., Terada, K., Minami, T., Yoshikawa, H. & Furukawa, T.
Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation.
BMC Developmental Biology, 9:70 (2009)
Cao, Y., Masuho, I., Okawa, H., Xie, K., Asami, J., Kammermeier, P., Maddox, D., Furukawa, T., Inoue, T., Sampath, A. & Martemyanov, K.
Retina Specific GTPase Accelerator RGS11/Gβ5S/R9AP is a Constitutive Heterotrimer Selectively Targeted to mGluR6 in ON-Bipolar Neurons.
J. of Neurosci., 29, 9301-9313 (2009)
Sasaki, T., Watanabe, W., Muranishi, Y., Kanamoto, T., Aibara M., Miyazaki, K., Tamura, H., Saeki, T., Oda, H., Souchelnytskyi, N., Souchelnytskyi, S., Aoyama, H., Honda, Z., Furukawa, T., Mishima. K. H., Kiuchi, Y. & Honda, H.
Elevated Intraocular Pressure, Optic Nerve Atrophy, and Impaired Retinal Development in ODAG Transgenic Mice.
IOVS, 50, No.1, 242-248 (2009)
Sato, S., Omori, Y., Katoh, K., Kondo, M., Kanagawa, M., Miyata, K., Funabiki, K., Koyasu, T., Kajimura, N., Miyoshi, T., Sawai, H., Kobayashi K., Tani, A., Toda, T., Usukura, J., Tano, Y., Fujikado, T., Furukawa,T.
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.
Nat Neuroscience, 11, 923-931 (2008)
Omori, Y., Zhao, C., Saras, A., Mukhopadhyay, S., Kim, W., Furukawa, T., Sengupta, P., Veraksa, A., Malicki, J.
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8.
Nat Cell Biol., 10, 434-444 (2008)
Koike, C., Nishida, A.,Ueno, S., Saito, H., Sanuki, R., Sato, S., Furukawa, A., Aizawa, S.,Matsuo, I., Suzuki, N., Kondo, M., Furukawa, T.
Functional roles of Otx2 transcription factor in postnatal mouse retinal development.
Mol. Cell Biol. 27, 8318-8329 (2007)
Sato, S., Inoue, T., Terada, K., Matsuo, I., Aizawa, S., Tano, Y., Fujikado, T., Furukawa, T.
Dkk3-Cre BAC trasngenic mouse line: A tool for hilghly efficient gene deletion in retinal progenitor cells.
Genesis, 45, 502-507 (2007)
Terada, K., Kitayama, A., Kanamoto, T., Ueno, N., Furukawa, T.
Nucleosome regulator Xhmgb3 is essential for progenitor cell proliferation of the eye and brain.
Developmental Biology, 291, 298-412 (2006)
Inoue, T., Terada, K., Furukawa, A., Koike, C., Tamaki, Y., Araie, M., Furukawa, T.
Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells.
BMC Developmental Biology, 6:15 (2006)
Kanamoto, T., Terada, K., Yoshikawa, H., Furukawa, T.
Cloning and regulation of the vertebrate homologue of lin-41 which functions as heterochronic gene in Caenorhabditis elegans.
Developmental Dynamics, 235, 1142-1149 (2006)
Kanamoto, T., Terada, K., Yoshikawa, H., Furukawa, T.
Cloning and expression pattern of lbx3, a novel chick homeobox gene.
Mechanisms of Development/Gene Expression Patterns, 6. 241-246 (2006)
Koike, C., Nishida, A., Akimoto K., Nakaya, M., Noda, T., Ohno, S., Furukawa, T.
Function of aPKCl in differentiating photoreceptors is required for proper lamination of mouse retina.
J. of Neurosci., 25, 10290-10298 (2005)
Saito, H., Tsumura, H., Otake, S., Nishida, A., Furukawa, T., Suzuki N.
L7/Pcp-2-specific expression of Cre recombinase using knock-in approach.
BBRC, 331, 1216-1221 (2005)
Morrow, E.M., Furukawa, T., Raviola, E., Cepko, C.L.
Synaptogenesis and outer segment formation are peturbed in the neural retina.
BMC Neuroscience, 6, 1471-2205 (2005)
Nishida, A., Furukawa, A., Koike, C., Tano, Y., Aizawa, S., Matsuo, I., Furukawa, T.
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.
Nature Neurosci., 6, 1255-1263 (2003)
Furukawa, A., Koike, C., Lippincott, P., Cepko, C.L., Furukawa, T.
The mouse Crx 5’ upstream transgene sequence directs a cell-specific and developmentally regulated expression in retinal photoreceptor cells.
J. of Neurosci., 22,1640-1647 (2002)
Blackshaw, S., Fraioli, R.E., Furukawa, T., Cepko, C.L.
Comprehensive Analysis of Photoreceptor Gene Expression and the Identification of Candidate Retinal disease Genes.
Cell, 107, 579-589 (2001)
Furukawa,T., Shiddartha, M., Bao, Z-Z, Morrow, E.M., Cepko, C.L.
rax, Hes1 and Notch1 promote the formation of Muller glia by postnatal retinal progenitor cells.
Neuron, 26, 383-394 (2000)
Livesey, F.J. Furukawa, T., Steffen, M., Church, G.M., Cepko, C.L
Microarray anaysis of the transcriptional netwaork controlled by the photoreceptor-specific homeobox gene Crx.
Curr Biol, 10, 301-310 (2000)
*Furukawa, T., Morrow, E.M., Li, T., Davis, F.C., *Cepko, C.L.
Retinopathy and attenuated circadian entrainment in Crx-deficient mice.
Nature Genet., 23, 466-470 (1999)
(*Corresponding author)
*Schulte, D., *Furukawa, T., *Peters, M.A., Kozak, C.A., Cepko, C.L. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map.
Neuron, 24, 541-553 (1999)
(*First three authors contributed equally to this work.)
Morrow, E.M., Furukawa, T., Lee. J.E., Cepko, C.L.
Neuro D regulates cell fate determination in the Developing neural retina.
Development, 126, 23-36 (1999)
Morrow, E.M., Furukawa, T., Cepko, C.L.
Vertebrate photoreceptor cell development and disease.
Trends in Cell Biol., 8, 353-358 (1998)
Taniguchi, Y., Furukawa, T., Tun, T., Han, H., Honjo, T.
LIM protein KyoT2 negatively regulates transcription by association with the RBP-JDNA-binding protein.
Mol Cell Biol., 18, 644-654 (1998)
Furukawa, T., Morrow, E.M., Cepko, C.L.
Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.
Cell, 91, 531-541 (1997)
*Freund, C.L., *Gregory-Evans, C.Y., *Furukawa, T., Papaioa
Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity. Proc Natl Acad Sci U S A. 2017.
Omori Y, Kubo S, Kon T, Furuhashi M, Narita H, Kominami T, Ueno A, Tsutsumi R, Chaya T, Yamamoto H, Suetake I, Ueno S, Koseki H, Nakagawa A and Furukawa T
Proc Natl Acad Sci U S A. 2017.
Title
Journal
Taro Chaya, Yamato Maeda, Ryo Sugimura, Haruka Yamamoto, Hidemasa Kato, Takahisa Furukawa
Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation
Journal of Biological Chemistry
https://doi.org/10.1016/j.jbc.2022.101686
https://www.jbc.org/article/S0021-9258(22)00735-9/fulltext
Ryotaro Tsutsumi, Taro Chaya, Toshinori Tsujii, Takahisa Furukawa
The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis
Journal of Biological Chemistry
https://doi.org/10.1016/j.jbc.2022.101686
https://www.jbc.org/article/S0021-9258(22)00126-0/fulltext
Taro Chaya, Hiroshi Ishikane, Leah R Varner, Yuko Sugita, Yamato Maeda, Ryotaro Tsutsumi, Daisuke Motooka, Daisuke Okuzaki, Takahisa Furukawa
Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity
HUMAN MOLECULAR GENETICS
https://doi.org/10.1093/hmg/ddab268
https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab268/6368510
Daichi Gyoten, Shinji Ueno, Satoshi Okado, Taro Chaya, Shunsuke Yasuda, Takeshi Morimoto, Mineo Kondo, Kazuhiro Kimura, Takaaki Hayashi, Bart P Leroy, Se Joon Woo, Ryo Mukai, Kwangsic Joo, Takahisa Furukawa
Broad locations of antigenic regions for anti-TRPM1 autoantibodies in paraneoplastic retinopathy with retinal ON bipolar cell dysfunction
Experimantal Eye Research
https://doi.org/10.1016/j.exer.2021.108770
https://www.sciencedirect.com/science/article/abs/pii/S0014483521003365?via%3Dihub
Shun Kubo, Haruka Yamamoto, Naoko Kajimura, Yoshihiro Omori, Yamato Maeda, Taro Chaya, Takahisa Furukawa
Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity
Scientific Reports
https://doi.org/10.1038/s41598-021-83781-1
https://www.nature.com/articles/s41598-021-83781-1
Takefumi Sugiyama, Haruka Yamamoto, Tetsuo Kon, Taro Chaya, Yoshihiro Omori, Yutaka Suzuki, Kentaro Abe, Dai Watanabe, Takahisa Furukawa
The potential role of Arhgef33 RhoGEF in foveal development in the zebra finch retina
Scientific Reports
https://doi.org/10.1038/s41598-020-78452-6
https://www.nature.com/articles/s41598-020-78452-6
Yuko Sugita, Haruka Yamamoto, Yamato Maeda, Takahisa Furukawa
Inluence of aging on the retina and visual motion processing for optokineic responses in mice
Frontiers in Neuroscience
https://doi.org/10.3389/fnins.2020.586013
https://www.frontiersin.org/articles/10.3389/fnins.2020.586013/full
Tetsuo Kon, Takahisa Furukawa
Origin and evolution of the Rax homeobox gene by comprehensive evolutionary analysis
FEBS open bio
https://doi.org/10.1002/2211-5463.12832
https://febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.12832
Yuko Sugita, Kenichiro Miura, Takahisa Furukawa
Retinal ON and OFF pathways contribute to initial optokinetic responses with different temporal characteristics
European Journal of Neuroscience
https://doi.org/10.1111/ejn.14697
https://onlinelibrary.wiley.com/doi/full/10.1111/ejn.14697?af=R
Haruka Yamamoto, Tetsuo Kon, Yoshihiro Omori, Takahisa Furukawa
Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development
Cell Reports
https://doi.org/10.1016/j.celrep.2019.212.072
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31729-2
Taro Chaya, Ryotaro Tsutsumi, Leah Rie Varner, Yamato Maeda, Satoyo Yoshida, Takahisa Furukawa
Cul3‐Klhl18 ubiquitin ligase modulates rod transducin translocation during light‐dark adaptation
EMBO J.
https://doi.org/10.15252/embj.2018101409
https://www.embopress.org/doi/10.15252/embj.2018101409
Takashi Kozuka, Yoshihiro Omori, Satoshi Watanabe, Etsuko Tarusawa, Haruka Yamamoto, Taro Chaya, Mayu Furuhashi, Makiko Morita, Tetsuya Sato, Shinichi Hirose, Yasuyuki Ohkawa, Yumiko Yoshimura, Takatoshi Hikida & Takahisa Furukawa
miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation
Scientific Reports
https://doi.org/10.1038/s41598-019-38910-2
https://www.nature.com/articles/s41598-019-38910-2
Ryotaro Tsutsumi, Taro Chaya, Takahisa Furukawa
Enriched expression of the ciliopathy gene Ick in cell proliferating regions of adult mice
Gene Expression Patterns
doi:10.1016/j.gep.2018.04.005
https://www.sciencedirect.com/science/article/pii/S1567133X18300140
Akiko Ueno, Yoshihiro Omori, Yuko Sugita, Satoshi Watanabe, Taro Chaya, Takashi Kozuka, Tetsuo Kon, Satoyo Yoshida, Kenji Matsushita, Ryusuke Kuwahara, Naoko Kajimura, Yasushi Okada, Takahisa Furukawa
Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity
Cell Reports 22, 3548–3561 March 27, 2018
doi:10.1016/j.celrep.2018.03.007
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30321-8
Michio Miyajima, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Matteo M Guerrini, Yumi Tsutsui, Mikako Maruya, Alexis Vogelzang, Kenji Chamoto, Kurara Honda, Takatoshi Hikida, Satomi Ito, Hongyan Qin, Rikako Sanuki, Keiichiro Suzuki, Takahisa Furukawa, Yasushi Ishihama, Fumihiko Matsuda, Makoto Suematsu, Tasuku Honjo and Sidonia Fagarasan
Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior
Nature Immunology.
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Kozuka T, Chaya T, Tamalu F, Shimada M, Fujimaki-Aoba K, Kuwahara R, Watanabe SI, Furukawa T.
The TRPM1 channel is required for development of the rod ON bipolar cell-AII amacrine cell pathway in the retinal circuit.
J Neurosci. 2017 Sep 12.
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Omori Y, Kubo S, Kon T, Furuhashi M, Narita H, Kominami T, Ueno A, Tsutsumi R, Chaya T, Yamamoto H, Suetake I, Ueno S, Koseki H, Nakagawa A and Furukawa T
Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity.
Proc Natl Acad Sci U S A. 2017.
Taro Chaya, Akihiro Matsumoto, Yuko Sugita, Satoshi Watanabe, Ryusuke Kuwahara, Masao Tachibana and Takahisa Furukawa
Versatile functional roles of horizontal cells in the retinal circuit.
Sci Rep. 2017 Jul 17;7(1):5540.
Okamoto S, Chaya T, Omori Y, Kuwahara R, Kubo S, Sakaguchi H and Furukawa T
Ick ciliary kinase is essential for planar cell polarity formation in inner ear hair cells and hearing function
J. of Neurosci, 2017, Feb 22;37(8): 2073-2085.
Irie S, Sanuki R, Muranishi Y, Kato K, Chaya T, Furukawa T
Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse Retina.
Mol Cell Biol 35:2583–2596.
doi:10.1128/MCB.00048-15.
Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T.
Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.
PLoS One. 2015 Jun 8;10(6):e0128422.
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Watanabe S, Sanuki R, Sugita Y, imai W, Yamazaki R, Kozuka T, Ohsuga M, Furukawa T.
Prdm13 Regulates Subtype Specification of Retinal Amacrine Interneurons and Modulates Visual Sensitivity.
J. of Neurosci, 2015, May 20;35(20): 8004-20.
Chaya T, Omori Y, Kuwahara R, Furukawa T.
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
EMBO J. 2014,
doi:10.1002/embj.201488175
Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW & Wijnholds J
Targeted ablation of Crb2 in Photoreceptor Cells induces Retinitis Pigmentosa.
Hum Mol Genet. 2014,
doi:10.1093/hmg/ddu048
Mizuhashi K, Kanamoto T, Moriishi T, Muranishi Y, Miyazaki T, Terada K, Omori Y, Ito M, Komori T, Furukawa T
Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.
Hum Mol Genet. 2014,
doi:10.1093/hmg/ddu007
Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A & Watanabe S
Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.
Proc Natl Acad Sci USA, 2014,111(10): 3751-3756.
Kanda A, Noda K, Yuki K, Ozawa Y, Furukawa T, Ichihara A & Ishida S
Atp6ap2/(Pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.
J. of Neurosci, 2013, 33(49): 19341-19351.
Yamazaki D, Funato Y, Miura J, Sato S, Toyosawa S, Furutani K, Kurachi Y, Omori Y, Furukawa T, Tsuda T, Kuwabata S, Mizukami S,Kikuchi K & Miki H
Basolateral Mg2+ Extrusion via CNNM4 Mediates, Transcellular Mg2+, Transport across Epithelia: A Mouse Model.
PLOS Gene. 2013, 9(12): e1003983.
Sugita Y, Miura K, Araki F, Furukawa T, Kawano & K.Eur
Contributions of retinal direction-selective ganglion cells to optokinetic responses in mice.
Eur J Neurosci. 2013, 38(6): 2823-31.
Eberhart A, Feodorava Y, Song C, Wanner G, Kiseleva E, Hake S, Furukawa T, Kimura H, Schotta G, Leonhardt H, Joffe B & Solovei I
Epigenetics of eu- and heterochromatin in inverted and conventional nuclei.
Chromosome Res. 2013, 20(5): 535-554.
Watanabe S, Sanuki R, Ueno S, Koyasu T, Hasegawa T, Furukawa T
Tropisms of AAV for subretinal delivery to the neonatal mouse retina and its application for in vivo rescue of developmental photoreceptor disorders.
PLoS One. 2013; 8(1):e54146.
Katoh K, Yamazaki R, Onishi A, Sanuki R, Furukawa T.
G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.
J. of Neurosci. 2012, Dec 5;32(49):17658-70.
Muranishi Y & Furukawa T
BAC-Dkk3-EGFP Transgenic Mouse: An In Vivo Analytical Tool for Dkk3 Expression.
J Biomed Biotechnol. 2012:973140.
Peachey NS, Pearring JN, Bojang P, Jr., Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, & Gregg RG
Depolarizing Bipolar Cell Dysfunction due to a Trpm1 Point Mutation.
J Neurophysiol. 2012, 108(9):2442-2451.
Ochocinska MJ, Muñoz EM, Veleri S, Weller JL, Coon SL, Pozdeyev N, Michael Iuvone P, Goebbels S, Furukawa T & Klein DC
NeuroD1 is required for survival of photoreceptors but not pinealocytes: Results from targeted gene deletion studies.
J Neurochem. 2012, 123(1):44-59.
Omori Y, Araki F, Chaya T, Kajimura N, Irie S, Terada K, Muranishi Y, Tsujii T, Ueno S, Koyasu T, Tamaki Y, Kondo M, Amano S, Furukawa T.
Presynaptic Dystroglycan-Pikachurin Complex Regulates the Proper Synaptic Connection between Retinal Photoreceptor and Bipolar Cells.
J. of Neurosci. 2012 May 2;32(18): 6126-6137.
Muranishi Y, Terada K, Inoue T, Katoh K, Tsujii T, Sanuki R, Kurokawa D, Aizawa S, Tamaki Y, Furukawa T.
An Essential Role for RAX Homeoprotein and NOTCH–HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination.
J. of Neurosci. 2011, 31(46): 16792-16807
Sanuki, R., Onishi, A., Koike C., Muramatsu R., Watanabe S., Muranishi Y., Irie S., Uneo S., Koyasu T., Matsui R., Chérasse Y., Urade Y., Watanabe D., Kondo M., Yamashita T. & Furukawa T.
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression, Nature Neuroscience, 14, 1125–1134 (2011)
Pearring, J., Bojang Jr., P., Shen, Y., Koike, C., Furukawa, T., Nawy, S. & Gregg, R.
A Role for Nyctalopin, a Small Leucine-Rich Repeat Protein, in Localizing the TRP Melastatin 1 Channel to Retinal Depolarizing Bipolar Cell Dendrites.
J. of Neurosci. 31(27), 10060-10066 (2011)
*Omori, Y., *Katoh, K., *Sato, S., Muranishi, Y., Chaya, T., Onishi, A., Minami, T., Fujikado, T., & Furukawa, T.
Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.
PLoS ONE, 6(5), e19685 (2011)
(*First three authors contributed equally to this work.)
*Kondo, M., *Sanuki, R., Ueno, S., Nishizawa, Y., Hashimoto, N., Ohguro, H., Yamamoto, S., Machida, S., Terasaki, H., Adamus, Grazyna., & Furukawa, T.,
Indentification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction.
PLoS ONE, 6(5), e19911 (2011)
(*These authors contributed equally to this work.)
Okada, I., Hamanoue, H., Terada, K., Tohma, T., Megarbane, A., Chouery, E., Abou Ghoch, J., Jalkh, N., Cogulu, O., Ozkinay, F., Horie, K., Takeda, J., Furuichi, T., Ikegawa, S., Nishiyama, K., Miyatake, S.,
Nishimura, A., Mizuguchi, T., Niikawa, N., Hirahara, F., Kaname, T., Yoshiura, K., Tsurusaki, Y., Doi, H., Miyake, N., Furukawa, T., Matsumoto, N. & Saitsu, H.
SMOC1 is essential for ocular and limb development in humans and mice.
Am. J. Hum. Genet.,88, 1-12 (2010)
Omori Y., Chaya T., Katoh K., Kajimura N., Sato S., Muraoka K., Ueno S., Koyasu T., Kondo M., & Furukawa T.
Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.
Proc. Natl. Acad. Sci. USA, 2010 Dec. 8
Katoh, K., Omori Y., Onishi A., Sato S., Kondo M. & Furukawa, T. Blimp1 Suppresses Chx10 Expression in Differentiating Retinal Photoreceptor Precursors to Ensure Proper Photoreceptor Development.
J. of Neurosci, 30(19):6515-6526 (2010)
Nakamura, M., Sanuki, R., Yasuma, R, T., Onishi, A., Nishiguchi, M, K., Kadowaki, M., Kondo, M., Miyake, Y. & Furukawa, T.
TRPM1 mutations are associated with the complete form of congenital stationary night blindness.
Mol. Vision 16:425-437 (2010)
Katahira, T., Nakagiri, S., Terada, K. & Furukawa, T.
Secreted factor FAM3C (ILEI) is involved in retinal laminar formation.
BBRC, 392(3), 301-306 (2010)
Muranishi, Y., Sato, S., Inoue, T., Ueno, S., Koyasu, T., Kondo, M. & Furukawa, T.
Gene expression analysis of embryonic photoreceptor precursor cells using BAC-Crx-EGFP transgenic mouse.
BBRC, 392(3), 317-322 (2010)
Sanuki, R., Omori, Y., Koike, C., Sato, S. & Furukawa, T.
Panky, a novel photoreceptor-specific ankyrin repeat protein, is a transcriptional cofactor that suppresses CRX-regulated photoreceptor genes.
FEBS Letters, 584, 753-758 (2009)
Koike, C., Obara, T., Uriu, Y., Numata, T., Sanuki, R., Miyata, K., Koyasu, T., Ueno, S., Funabiki, K., Tani, A., Ueda, H., Kondo, M., Mori Y., Tachibana, M. & Furukawa, T.
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.
Proc. Natl. Acad. Sci. USA, 2009 Dec.4. Epub ahead of print (2009)
Kanamoto, T., Mizuhashi, K., Terada, K., Minami, T., Yoshikawa, H. & Furukawa, T.
Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation.
BMC Developmental Biology, 9:70 (2009)
Cao, Y., Masuho, I., Okawa, H., Xie, K., Asami, J., Kammermeier, P., Maddox, D., Furukawa, T., Inoue, T., Sampath, A. & Martemyanov, K.
Retina Specific GTPase Accelerator RGS11/Gβ5S/R9AP is a Constitutive Heterotrimer Selectively Targeted to mGluR6 in ON-Bipolar Neurons.
J. of Neurosci., 29, 9301-9313 (2009)
Sasaki, T., Watanabe, W., Muranishi, Y., Kanamoto, T., Aibara M., Miyazaki, K., Tamura, H., Saeki, T., Oda, H., Souchelnytskyi, N., Souchelnytskyi, S., Aoyama, H., Honda, Z., Furukawa, T., Mishima. K. H., Kiuchi, Y. & Honda, H.
Elevated Intraocular Pressure, Optic Nerve Atrophy, and Impaired Retinal Development in ODAG Transgenic Mice.
IOVS, 50, No.1, 242-248 (2009)
Sato, S., Omori, Y., Katoh, K., Kondo, M., Kanagawa, M., Miyata, K., Funabiki, K., Koyasu, T., Kajimura, N., Miyoshi, T., Sawai, H., Kobayashi K., Tani, A., Toda, T., Usukura, J., Tano, Y., Fujikado, T., Furukawa,T.
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.
Nat Neuroscience, 11, 923-931 (2008)
Omori, Y., Zhao, C., Saras, A., Mukhopadhyay, S., Kim, W., Furukawa, T., Sengupta, P., Veraksa, A., Malicki, J.
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8.
Nat Cell Biol., 10, 434-444 (2008)
Koike, C., Nishida, A.,Ueno, S., Saito, H., Sanuki, R., Sato, S., Furukawa, A., Aizawa, S.,Matsuo, I., Suzuki, N., Kondo, M., Furukawa, T.
Functional roles of Otx2 transcription factor in postnatal mouse retinal development.
Mol. Cell Biol. 27, 8318-8329 (2007)
Sato, S., Inoue, T., Terada, K., Matsuo, I., Aizawa, S., Tano, Y., Fujikado, T., Furukawa, T.
Dkk3-Cre BAC trasngenic mouse line: A tool for hilghly efficient gene deletion in retinal progenitor cells.
Genesis, 45, 502-507 (2007)
Terada, K., Kitayama, A., Kanamoto, T., Ueno, N., Furukawa, T.
Nucleosome regulator Xhmgb3 is essential for progenitor cell proliferation of the eye and brain.
Developmental Biology, 291, 298-412 (2006)
Inoue, T., Terada, K., Furukawa, A., Koike, C., Tamaki, Y., Araie, M., Furukawa, T.
Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells.
BMC Developmental Biology, 6:15 (2006)
Kanamoto, T., Terada, K., Yoshikawa, H., Furukawa, T.
Cloning and regulation of the vertebrate homologue of lin-41 which functions as heterochronic gene in Caenorhabditis elegans.
Developmental Dynamics, 235, 1142-1149 (2006)
Kanamoto, T., Terada, K., Yoshikawa, H., Furukawa, T.
Cloning and expression pattern of lbx3, a novel chick homeobox gene.
Mechanisms of Development/Gene Expression Patterns, 6. 241-246 (2006)
Koike, C., Nishida, A., Akimoto K., Nakaya, M., Noda, T., Ohno, S., Furukawa, T.
Function of aPKCl in differentiating photoreceptors is required for proper lamination of mouse retina.
J. of Neurosci., 25, 10290-10298 (2005)
Saito, H., Tsumura, H., Otake, S., Nishida, A., Furukawa, T., Suzuki N.
L7/Pcp-2-specific expression of Cre recombinase using knock-in approach.
BBRC, 331, 1216-1221 (2005)
Morrow, E.M., Furukawa, T., Raviola, E., Cepko, C.L.
Synaptogenesis and outer segment formation are peturbed in the neural retina.
BMC Neuroscience, 6, 1471-2205 (2005)
Nishida, A., Furukawa, A., Koike, C., Tano, Y., Aizawa, S., Matsuo, I., Furukawa, T.
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.
Nature Neurosci., 6, 1255-1263 (2003)
Furukawa, A., Koike, C., Lippincott, P., Cepko, C.L., Furukawa, T.
The mouse Crx 5’ upstream transgene sequence directs a cell-specific and developmentally regulated expression in retinal photoreceptor cells.
J. of Neurosci., 22,1640-1647 (2002)
Blackshaw, S., Fraioli, R.E., Furukawa, T., Cepko, C.L.
Comprehensive Analysis of Photoreceptor Gene Expression and the Identification of Candidate Retinal disease Genes.
Cell, 107, 579-589 (2001)
Furukawa,T., Shiddartha, M., Bao, Z-Z, Morrow, E.M., Cepko, C.L.
rax, Hes1 and Notch1 promote the formation of Muller glia by postnatal retinal progenitor cells.
Neuron, 26, 383-394 (2000)
Livesey, F.J. Furukawa, T., Steffen, M., Church, G.M., Cepko, C.L
Microarray anaysis of the transcriptional netwaork controlled by the photoreceptor-specific homeobox gene Crx.
Curr Biol, 10, 301-310 (2000)
*Furukawa, T., Morrow, E.M., Li, T., Davis, F.C., *Cepko, C.L.
Retinopathy and attenuated circadian entrainment in Crx-deficient mice.
Nature Genet., 23, 466-470 (1999)
(*Corresponding author)
*Schulte, D., *Furukawa, T., *Peters, M.A., Kozak, C.A., Cepko, C.L. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map.
Neuron, 24, 541-553 (1999)
(*First three authors contributed equally to this work.)
Morrow, E.M., Furukawa, T., Lee. J.E., Cepko, C.L.
Neuro D regulates cell fate determination in the Developing neural retina.
Development, 126, 23-36 (1999)
Morrow, E.M., Furukawa, T., Cepko, C.L.
Vertebrate photoreceptor cell development and disease.
Trends in Cell Biol., 8, 353-358 (1998)
Taniguchi, Y., Furukawa, T., Tun, T., Han, H., Honjo, T.
LIM protein KyoT2 negatively regulates transcription by association with the RBP-JDNA-binding protein.
Mol Cell Biol., 18, 644-654 (1998)
Furukawa, T., Morrow, E.M., Cepko, C.L.
Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.
Cell, 91, 531-541 (1997)
*Freund, C.L., *Gregory-Evans, C.Y., *Furukawa, T., Papaioa
Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity. Proc Natl Acad Sci U S A. 2017.
Omori Y, Kubo S, Kon T, Furuhashi M, Narita H, Kominami T, Ueno A, Tsutsumi R, Chaya T, Yamamoto H, Suetake I, Ueno S, Koseki H, Nakagawa A and Furukawa T
Proc Natl Acad Sci U S A. 2017.