People

Endowed Chair and Professor
Kiyotoshi SEKIGUCHI
E-mail: protein.osaka-u.ac.jp
Research interests: cell-matrix interactions, basement membranes, integrins, designer matrix for stem cells, Angiopoietin-Tie system

Kiyotoshi Sekiguchi is currently Nippi Endowed Chair and Professor of Institute for Protein Research at Osaka University. He was born in 1950 and grew up in Hokkaido until he moved to Tokyo in 1961. He graduated from Tokyo Institute of Technology in 1973 with a bachelor's degree in chemistry and received his Ph.D. in biochemistry from Osaka University in 1978. Kiyotoshi did post-doctoral work at Fred Hutchinson Cancer Research Center in Seattle, Washington, with Sen-itiroh Hakomori, investigating the domain structure of fibronectin from 1979 through 1986. He was Assistant and then Associate Professor of Institute for Comprehensive Medical Science at Fujita Health University, and the Director of Research Institute, Osaka Medical Center for Maternal and Child Health, before he became Professor at Institute for Protein Research, Osaka University in 1998. His current research focuses on the structure and function of cell-adhesive proteins and engineering of 2D and 3D matrices for stem cells in regenerative medicine. He served as the Director of ERATO Sekiguchi Biomatrix Signaling Project (1999-2006) funded by Japan Science and Technology Agency and constructed a high-resolution immunohistochemical image database for more than 40 basement membrane proteins including all laminin subunits, which is named "Mouse Basement Membrane Bodymap" available on the web at http://dbarchive.biosciencedbc.jp/archive/matrixome/bm/home.html.

Endowed Associate Professor
Yukimasa TANIGUCHI
E-mail: protein.osaka-u.ac.jp
Project: Biochemical/cell biological analyses of cell-basement membrane interactions and their application to regenerative medicine
Keywords: basement membrane proteins, integrins, proteoglycans, stem cells, 3D culture, regenerative medicine, protein designing
Specially Appointed Researcher
Shaoliang LI
E-mail: protein.osaka-u.ac.jp
研究テーマ:Development of culture matrix for stem cells
キーワード:basement membrane protein, construction of multifunctional protein, three-dimensional culture
Visiting Researcher
Yasuhiro SHIMIZU
E-mail: protein.osaka-u.ac.jp
Project: Production and validation of secreted recombinant proteins
Keywords: production of chimeric protein, glycosaminoglycan; ELISA, surface plasmon resonance, regenerative medicine
Visiting Researcher
Masamichi DOIGUCHI
E-mail: protein.osaka-u.ac.jp
Project: Role of Polydom in adipose stem cells
Keywords: extracellular matrix, Polydom, mesenchymal stem cell
Visiting Researcher
Fumi EBISU
E-mail: protein.osaka-u.ac.jp
Project: Microcarrier culture systems for hPSCs and differentiated cells
Keywords: human iPS cell, microcarrier culture system, non-enzymatic EDTA detachment method
Visiting Researcher
Ayano ISHIMARU
E-mail: protein.osaka-u.ac.jp
Project: Next generation 3D matrix for regenerative medicine
Keywords: basement membrane proteins and their receptors, proteoglycan, stem cells, three-dimensional culture
Visiting Researcher
Kohei MINOBE
E-mail: protein.osaka-u.ac.jp
Project: Microcarrier culture systems for hPSCs and differentiated cells
Keywords: human iPS cell, microcarrier culture system, non-enzymatic EDTA detachment method
Visiting Researcher
Ayaka HADA
E-mail: protein.osaka-u.ac.jp
Project: Next generation 3D matrix for regenerative medicine
Keywords: laminin, integrin, 3D culture system, organoid
Lab Technician
Taiko KUNIEDA
E-mail: protein.osaka-u.ac.jp
Project: Protein purification and biochemical assays
Keywords: liquid chromatography, SDS-PAGE, western blotting
Administrative Staff
Kayoko FUJITA
E-mail: protein.osaka-u.ac.jp
Kayoko supports lab members so that they can carry out their research activities smoothly.